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KMID : 0357220000120030319
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Journal of Korean Society Physical Therapy
2000 Volume.12 No. 3 p.319 ~ p.330
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The Effects of Pulsed Electromagnetic Energy and Microcurrent on Wound Healing in Rabbits
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권원안/Kwon, Won-An
박래준/박윤기/황태연/Park, Rae-Joon/Park, Youn-Ki/Hwang, Tae-Yeun
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Abstract
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The purpose of this study was to evaluate the effects of pulsed electromagnetic energy (Diapulse) and micro current on the wound healing in rabbits. 15 domestic rabbits were randomly assigned to the PEME(n=5),
MC(n=5) and CON(n=5) group. Each rabbits were anesthetized with lidocaine HCL 2%. Skin wounds were created laterally on the back of 15 domestic rabbits(3 3cm). From 24 hours after being knitted, the rabbits of the PEME group were irradiated with an intensity of 3 at a 300 pulses per second, which, were applied for 15 minutes every day during the 12 days. The MC group were stimulated with an intensity of 50uA at frequency of 40 pulses per second, which were applied for 15 minutes every day during the 12 days. The CON group were not stimulated. The rabbits were sacrificed and the incised wound parts were processed appropriately for the light microscopic examination on the 3rd day, 6th day and 12th day before the beginning of wound treatment. The areas of wound were measured with metric graph paper.
The results were as follows.
1. The PEME and MC group compared with control group showed that wound closure rate increased on 6th, 12th day.
2. It was found that the CON group did not show a complete maturation and had a chronic inflammatory response. Judging from the irregularity of intercellular space and the loose, alignment of connective tissue, these findings showed that wound healing was delayed. 3. It showed that inflammatory cells, fibroblasts and epithelial cells activity rapidly processed in the PEME group compared with the CON group. It was found that the PEME group showed a advanced remodeling of epithelial layer and a positive repair of connective tissue.
4. It showed that fibroblasts, epithelial cells and inflammatory cells activity rapidly processed in the MC group compared with the CON group. It was found that the MC group showed a improved remodeling of
epithelial layer and a dense connective tissue.
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KEYWORD
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